Categorical data were expressed as numbers. Continuous data were expressed as medians and ranges. Cox proportional hazards regression analyses were used to identify factors associated with the development of HCC within 5 years of achieving SVR. Cumulative HCC incidence rates were generated using the Kaplan–Meier method and compared using the log-rank test. A receiver operating characteristic (ROC) curve was used to determine the optimal cutoff value of the new formula score for predicting HCC. Statistical significance was set at p < 0.05.>
Patient characteristics
The players included 172 men and you can 127 women. The latest average patient ages was 68 decades (range: 27–ninety decades). The average observance several months is actually 30 weeks (range: step one.0–72.0 days) following completion of SVR. New DAA cures regimens was basically daclatasvir/asunaprevir within the 41 clients, elbasvir/grazoprevir within the 36, glecaprevir/pibrentasvir in 63, sofosbuvir/ledipasvir during the 47, ombitasvir/paritaprevir/ritonavir ± ribavirin within the 65, and sofosbuvir/ribavirin for the 47 customers. New average platelet matter through to the start of DAA cures was 154?10 step 3 /?L (47–496?10 step three /?L), FIB-4 Directory PowerPoint slip larger photo fresh visualize Dining table step one. Baseline attributes of the customers.
Collective HCC incidence is actually cuatro.3% on 12 months, nine.7% within 36 months, and you will 12.5% from the 5 years pursuing the achievement away from SVR (Fig step one). Read More